Protein：High affinity immunoglobulin epsilon receptor subunit alpha

Gene:FCER1A

Organism:Homo sapiens (Human)

Binds to the Fc region of immunoglobulins epsilon. High affinity receptor. Responsible for initiating the allergic response. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators (such as histamine) responsible for the manifestations of allergy. The same receptor also induces the secretion of important lymphokines.(P12319 )