Telomerase reverse transcriptase (TERT, or hTERT in human) is a catalytic subunit of the enzyme telomerase, Ectopic expression of telomerase in telomerase-silent cells is sufficient to overcome senescence and to extend cellular lifespan, and has been used for cell immortalization. This lentivirus expresses hTERT under the control of CMV promoter and has neomycin as a selection marker.
 

Virus:hTERT lentivirus (CMV, Neo)

Titer (approx):1 x 108 TU/ml

Vector Information:Vector includes both 5’ and 3’ lentiviral LTR and all necessary elements for effective transduction; woodchuck hepatitis virus posttranscriptional regulatory element (WPRE)

Promoter for Target Gene:CMV

Target Gene / Reporter(s):hTert

Selection Gene:Neomycin

Biosafety Level:BSL-2

Shipped:Dry ice

Storage:Store at -80°C