Telomerase reverse transcriptase (TERT, or hTERT in human) is a catalytic subunit of the enzyme telomerase, Ectopic expression of telomerase in telomerase-silent cells is sufficient to overcome senescence and to extend cellular lifespan, and has been used for cell immortalization. This lentivirus expresses hTERT and GFP under the control of CMV promoter and has puromycin as a selection marker.
Virus:hTERT lentivirus (UBC, GFP, Puro)
Titer (approx):1 x 108 TU/ml
Vector Information:Vector includes both 5’ and 3’ lentiviral LTR and all necessary elements for effective transduction; woodchuck hepatitis virus posttranscriptional regulatory element (WPRE)
Promoter for Target Gene:UBC
Target Gene / Reporter(s):hTert, GFP
Selection Gene:Puromycin
Biosafety Level:BSL-2
Shipped:Dry ice
Storage:Store at -80°C